Microreactor with Thousands of Subcompartments: Enzyme-Loaded Liposomes within Polymer Capsules

Microreactor with Thousands of Subcompartments: Enzyme-Loaded Liposomes within Polymer Capsules

Fully loaded: Noncovalent anchoring of liposomes into polymer multilayered films with cholesterol-modified polymers allows the preparation of capsosomes--liposome-compartmentalized polymer capsules (see picture). A quantitative enzymatic reaction confirmed the presence of active cargo within the cap...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie (International ed.) 2009-01, Vol.48 (24), p.4359-4362
Hauptverfasser: Städler, Brigitte, Chandrawati, Rona, Price, Andrew D, Chong, Siow-Feng, Breheney, Kerry, Postma, Almar, Connal, Luke A, Zelikin, Alexander N, Caruso, Frank
Format: Artikel
Sprache:eng
Schlagworte:
beta-Lactamases - chemistry
beta-Lactamases - metabolism
Capsules
cross‐linking
enzymes
liposomes
Liposomes - chemistry
Octoxynol - chemistry
polymers
Polymers - chemistry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Fully loaded: Noncovalent anchoring of liposomes into polymer multilayered films with cholesterol-modified polymers allows the preparation of capsosomes--liposome-compartmentalized polymer capsules (see picture). A quantitative enzymatic reaction confirmed the presence of active cargo within the capsosomes and was used to determine the number of subcompartments within this novel biomedical carrier system.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200900386