Gammadelta and alphabeta T-cell acute lymphoblastic leukemia: comparison of their clinical and immunophenotypic features

Gammadelta-T-cell acute lymphoblastic leukemia (ALL) is a rare variant of ALL. The comparison of some clinical and laboratory features in children and adults with gammadelta-T-ALL or alphabeta-ALL showed that in gammadelta-T-ALL the CD45RAEth/CD45RO+ phenotype was predominant, the hemoglobin concent...

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Veröffentlicht in:	Haematologica (Roma) 2005-02, Vol.90 (2), p.264-266
Hauptverfasser:	Matos, DM, Rizzatti, EG, Fernandes, M, Buccheri, V, Falcao, RP
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Child Child, Preschool Female Hemoglobins - metabolism Humans Immunophenotyping - methods Infant Leukocyte Common Antigens - biosynthesis Male Phenotype Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology Receptors, Antigen, T-Cell, alpha-beta - metabolism Receptors, Antigen, T-Cell, gamma-delta - metabolism Splenomegaly - pathology
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Zusammenfassung:	Gammadelta-T-cell acute lymphoblastic leukemia (ALL) is a rare variant of ALL. The comparison of some clinical and laboratory features in children and adults with gammadelta-T-ALL or alphabeta-ALL showed that in gammadelta-T-ALL the CD45RAEth/CD45RO+ phenotype was predominant, the hemoglobin concentration was lower in children and the presence of splenomegaly and the white cell counts was higher in adults.
ISSN:	0390-6078 1592-8721