DNA and RNA Synthesis:  Antifolates

DNA and RNA Synthesis:  Antifolates

Kompis, Islam and Then discuss the major progress and developments in inhibitors of the enzymes involved in folic acid biosynthesis from Jan 1995 till mid-2004.

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Veröffentlicht in:Chemical reviews 2005-02, Vol.105 (2), p.593-620
Hauptverfasser: Kompis, Ivan M, Islam, Khalid, Then, Rudolf L
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
Deoxyribonucleic acid
DNA
DNA - biosynthesis
Drug Resistance, Microbial
Drug Resistance, Neoplasm
Enzymes
Folic Acid Antagonists - chemistry
Folic Acid Antagonists - pharmacology
Humans
Inhibitor drugs
Molecular Structure
Ribonucleic acid
RNA
RNA - biosynthesis
Tetrahydrofolate Dehydrogenase - metabolism
Vitamin B
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Beschreibung
Zusammenfassung:Kompis, Islam and Then discuss the major progress and developments in inhibitors of the enzymes involved in folic acid biosynthesis from Jan 1995 till mid-2004.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr0301144