Synthesis of Isoquinoline Derivatives Using ROM−RCM of Cyclobutene-yne

Isoquinoline derivatives were synthesized from cyclobutenylmethylamine derivatives having an alkyne moiety in a tether using a second-generation ruthenium carbene complex under ethylene gas in good yields.

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Veröffentlicht in:Journal of organic chemistry 2005-02, Vol.70 (3), p.1066-1069
Hauptverfasser: Mori, Miwako, Wakamatsu, Hideaki, Tonogaki, Keisuke, Fujita, Reiko, Kitamura, Tsuyoshi, Sato, Yoshihiro
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Sprache:eng
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Zusammenfassung:Isoquinoline derivatives were synthesized from cyclobutenylmethylamine derivatives having an alkyne moiety in a tether using a second-generation ruthenium carbene complex under ethylene gas in good yields.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo048214c