Proneness to psychological distress and risk of Alzheimer disease in a biracial community

Persons without dementia residing in a biracial community completed a brief scale of proneness to psychological distress, and 1,064 were subsequently examined for incident Alzheimer disease (AD) 3 to 6 years later. In analyses controlling for selected demographic and clinical variables, persons pron...

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Veröffentlicht in:	Neurology 2005-01, Vol.64 (2), p.380-382
Hauptverfasser:	WILSON, R. S, BARNES, L. L, BENNETT, D. A, LI, Y, BIENIAS, J. L, MENDES DE LEON, C. F, EVANS, D. A
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans - psychology Aged Alzheimer Disease - epidemiology Biological and medical sciences Chicago - epidemiology Cohort Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Susceptibility European Continental Ancestry Group - psychology Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Incidence Male Medical sciences Nervous system (semeiology, syndromes) Neurology Risk Sampling Studies Stress, Psychological - epidemiology
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Zusammenfassung:	Persons without dementia residing in a biracial community completed a brief scale of proneness to psychological distress, and 1,064 were subsequently examined for incident Alzheimer disease (AD) 3 to 6 years later. In analyses controlling for selected demographic and clinical variables, persons prone to distress were 2.4 times more likely to develop AD than persons not distress prone. This effect was substantially stronger in white persons compared to African Americans.
ISSN:	0028-3878 1526-632X
DOI:	10.1212/01.WNL.0000149525.53525.E7