Cardiovascular magnetic resonance in cardiac amyloidosis

Cardiac amyloidosis can be diagnostically challenging. Cardiovascular magnetic resonance (CMR) can assess abnormal myocardial interstitium. Late gadolinium enhancement CMR was performed in 30 patients with cardiac amyloidosis. In 22 of these, myocardial gadolinium kinetics with T1 mapping was compar...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2005-01, Vol.111 (2), p.186-193
Hauptverfasser:	MACEIRA, Alicia Maria, JOSHI, Jayshree, SANJAY KUMAR PRASAD, MOON, James Charles, PERUGINI, Enrica, HARDING, Idris, SHEPPARD, Mary Noelle, POOLE-WILSON, Philip Alexander, HAWKINS, Philip Nigel, PENNELL, Dudley John
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amyloidosis - diagnosis Amyloidosis - diagnostic imaging Amyloidosis - pathology Biological and medical sciences Biopsy Blood and lymphatic vessels Cardiology. Vascular system Cardiomyopathies - diagnosis Cardiomyopathies - diagnostic imaging Cardiomyopathies - pathology Contrast Media - pharmacokinetics Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Gadolinium DTPA - blood Gadolinium DTPA - pharmacokinetics Heart Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Hypertension - pathology Hypertrophy, Left Ventricular - diagnostic imaging Hypertrophy, Left Ventricular - etiology Hypertrophy, Left Ventricular - pathology Iodine Radioisotopes - pharmacokinetics Magnetic Resonance Imaging Male Medical sciences Middle Aged Neuropharmacology Organ Size Pharmacology. Drug treatments Prospective Studies Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Radionuclide Imaging Serum Amyloid P-Component - pharmacokinetics Stroke Volume Ultrasonography Ventricular Dysfunction, Left - etiology Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:	Cardiac amyloidosis can be diagnostically challenging. Cardiovascular magnetic resonance (CMR) can assess abnormal myocardial interstitium. Late gadolinium enhancement CMR was performed in 30 patients with cardiac amyloidosis. In 22 of these, myocardial gadolinium kinetics with T1 mapping was compared with that in 16 hypertensive controls. One patient had CMR and autopsy only. Subendocardial T1 in amyloid patients was shorter than in controls (at 4 minutes: 427+/-73 versus 579+/-75 ms; P
ISSN:	0009-7322 1524-4539
DOI:	10.1161/01.cir.0000152819.97857.9d