Developing new molecular imaging probes for PET

Developing new molecular imaging probes for PET

Positron emission tomography (PET) is a fully translational molecular imaging technique that requires specific probes radiolabelled with short-lived positron emitting radionuclides. This review discusses relevant methods which are applied throughout the different steps in the development of new PET...

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Veröffentlicht in:Methods (San Diego, Calif.) Calif.), 2009-06, Vol.48 (2), p.104-111
Hauptverfasser: Serdons, Kim, Verbruggen, Alfons, Bormans, Guy M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Carbon-11
Copper-64
Diagnostic Imaging - methods
Drug development
Fluorine-18
Gallium-68
Humans
Iodine-124
Isotope Labeling - methods
Molecular Diagnostic Techniques - methods
Molecular imaging
Molecular Probes
PET
Positron emission tomography
Positron-Emission Tomography - instrumentation
Positron-Emission Tomography - methods
Radioisotopes
Radiopharmaceutical
Radiopharmaceuticals
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Beschreibung
Zusammenfassung:Positron emission tomography (PET) is a fully translational molecular imaging technique that requires specific probes radiolabelled with short-lived positron emitting radionuclides. This review discusses relevant methods which are applied throughout the different steps in the development of new PET probes for in vivo visualization of specific molecular targets related to diagnosis or important for drug development.
ISSN:1046-2023
1095-9130
DOI:10.1016/j.ymeth.2009.03.010