One‐year results of basiliximab induction and tacrolimus associated with sequential steroid and MMF treatment in pediatric kidney transplant recipient

Summary We report the 1‐year results with a triple immunosuppressive regimen in pediatric recipients of a first kidney transplant, in order to evaluate its safety and efficacy in the prevention of acute rejection and in the reduction of steroid side effects. The immunosuppression is as follows: (i)...

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Veröffentlicht in:	Transplant international 2005-01, Vol.18 (1), p.36-42
Hauptverfasser:	Montini, Giovanni, Murer, Luisa, Ghio, Luciana, Pietrobon, Beatrice, Ginevri, Fabrizio, Ferraresso, Mariano, Cardillo, Massimo, Scalamogna, Mario, Perfumo, Francesco, Edefonti, Alberto, Zanon, Giovanni Franco, Zacchello, Graziella
Format:	Artikel
Sprache:	eng
Schlagworte:	acute rejection Adolescent Adrenal Cortex Hormones - therapeutic use Adult Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - therapeutic use Banff classification basiliximab Biological and medical sciences Biopsy Blood Glucose - metabolism Child Child, Preschool children Drug Administration Schedule General aspects Graft Rejection - drug therapy Graft Rejection - epidemiology Graft Rejection - prevention & control Graft Survival Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - therapeutic use kidney transplantation Kidney Transplantation - immunology Kidney Transplantation - pathology Medical sciences mycophenolate mofetil Mycophenolic Acid - administration & dosage Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use Nephrology. Urinary tract diseases Pharmacology. Drug treatments Recombinant Fusion Proteins - administration & dosage Recombinant Fusion Proteins - therapeutic use renal transplantation routine biopsies steroid withdrawal Survival Rate tacrolimus Tacrolimus - administration & dosage Tacrolimus - therapeutic use
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Zusammenfassung:	Summary We report the 1‐year results with a triple immunosuppressive regimen in pediatric recipients of a first kidney transplant, in order to evaluate its safety and efficacy in the prevention of acute rejection and in the reduction of steroid side effects. The immunosuppression is as follows: (i) basiliximab (20 mg if body weight >30 kg; 10 mg if
ISSN:	0934-0874 1432-2277
DOI:	10.1111/j.1432-2277.2004.00003.x