Autologous bone marrow transplantation as consolidation therapy in the treatment of adult patients under 60 years with acute myeloid leukaemia in first complete remission: a prospective randomized Dutch–Belgian Haemato‐Oncology Co‐operative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK) trial

Autologous bone marrow transplantation as consolidation therapy in the treatment of adult patients under 60 years with acute myeloid leukaemia in first complete remission: a prospective randomized Dutch–Belgian Haemato‐Oncology Co‐operative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK) trial

Summary The question as to whether autologous stem cell transplantation (SCT) after consolidation chemotherapy improves the probability of survival of patients with acute myeloid leukaemia (AML) in first remission has not been settled. Here, we present the results of a phase III study conducted in n...

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Veröffentlicht in:British journal of haematology 2005-01, Vol.128 (1), p.59-65
Hauptverfasser: Breems, Dimitri A., Boogaerts, Marc A., Dekker, Adriaan W., Van Putten, Wim L. J., Sonneveld, Pieter, Huijgens, Peter C., Van der Lelie, Johannes, Vellenga, Edo, Gratwohl, Alois, Verhoef, Gregor E. G., Verdonck, Leo F., Löwenberg, Bob
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
acute myeloid leukaemia
Adult
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
autologous stem cell transplantation
Belgium
Biological and medical sciences
Combined Modality Therapy
consolidation therapy
Disease-Free Survival
Female
first complete remission
Follow-Up Studies
Hematologic and hematopoietic diseases
Hematology
Humans
Leukemia, Myeloid - drug therapy
Leukemia, Myeloid - immunology
Leukemia, Myeloid - surgery
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Netherlands
phase III trial
Prospective Studies
Remission Induction
Stem Cell Transplantation
Survival Rate
Transplantation, Autologous
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Zusammenfassung:Summary The question as to whether autologous stem cell transplantation (SCT) after consolidation chemotherapy improves the probability of survival of patients with acute myeloid leukaemia (AML) in first remission has not been settled. Here, we present the results of a phase III study conducted in newly diagnosed adult AML patients aged
ISSN:0007-1048
1365-2141
DOI:10.1111/j.1365-2141.2004.05282.x