"Smart dust" biosensors powered by biomolecular motors

"Smart dust" biosensors powered by biomolecular motors

The concept of a microfabricated biosensor for environmental and biomedical monitoring applications which is composed of environmentally benign components is presented. With a built-in power source (the biological fuel ATP) and driven by biological motors (kinesin), sensing in the microdevice can be...

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Veröffentlicht in:Lab on a chip 2009-06, Vol.9 (12), p.1661-1666
Hauptverfasser: Bachand, George D, Hess, Henry, Ratna, Banahalli, Satir, Peter, Vogel, Viola
Format: Artikel
Sprache:eng
Schlagworte:
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
Equipment Design
Feasibility Studies
Kinesin - metabolism
Microtechnology
Reproducibility of Results
Sensitivity and Specificity
Time Factors
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Zusammenfassung:The concept of a microfabricated biosensor for environmental and biomedical monitoring applications which is composed of environmentally benign components is presented. With a built-in power source (the biological fuel ATP) and driven by biological motors (kinesin), sensing in the microdevice can be remotely activated and the presence of a target molecule or toxin remotely detected. The multifaceted progress towards the realization of such a device is described.
ISSN:1473-0197
DOI:10.1039/b821055a