Predicting asthma control using patient attitudes toward medical care: the REACT Score

Background The association between patients' degree of asthma control and their attitudes toward medical professionals and asthma therapy is unknown. Objective To develop a tool, the REACT Score, that can be used by physicians to compute the risk of having uncontrolled asthma based on patient attitudes toward medical professionals and asthma treatment. Methods A nationally representative sample of adult patients (≥18 years old) with moderate to severe asthma completed the Asthma Control Test and were surveyed regarding their attitudes about relationships with medical professionals and asthma treatments. Competing predictive models were developed to determine the association between attitude questions and asthma control. Using the model with the highest c-index, a REACT Score was computed. Results The proportion of uncontrolled patients (Asthma Control Test score