High-Content Peptide Microarrays for Deciphering Kinase Specificity and Biology

Thousands of kinase assays at one stroke are possible by using high‐content peptide microarrays. Such experiments deliver information regarding peptidic kinase substrates and accelerate the development of high‐throughput screening assays. Moreover, knowledge‐based selection of human sequences allows...

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Veröffentlicht in:	Angewandte Chemie International Edition 2004-05, Vol.43 (20), p.2671-2674
Hauptverfasser:	Schutkowski, Mike, Reimer, Ulf, Panse, Sören, Dong, Liying, Lizcano, Jose M., Alessi, Dario R., Schneider-Mergener, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Automation Binding Sites Electrophoresis, Polyacrylamide Gel enzymes high-throughput screening microarrays peptides Peptides - analysis Peptides - metabolism Phosphotransferases - analysis Phosphotransferases - metabolism Protein Array Analysis - methods Substrate Specificity
Online-Zugang:	Volltext
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