Interleukin 17 Production among Patients with American Cutaneous Leishmaniasis

Interleukin 17 (IL‐17) plays a critical role in inflammation and autoimmunity. Very little is known about IL‐17 in protozoa infection. Here, we show that lymphocytes obtained from patients with mucosal leishmaniasis and cutaneous leishmaniasis produce higher levels of IL‐17 than do lymphocytes obtai...

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Veröffentlicht in:	The Journal of infectious diseases 2009-07, Vol.200 (1), p.75-78
Hauptverfasser:	Bacellar, Olívia , Faria, Daniela , Nascimento, Márcia , Cardoso, Thiago M. , Gollob, Kenneth J. , Dutra, Walderez O. , Scott, Phillip , Carvalho, Edgar M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Autoimmunity Biological and medical sciences Cutaneous leishmaniasis Cytokines Fundamental and applied biological sciences. Psychology Humans Infections Infectious diseases Inflammation - immunology Interleukin-17 - genetics Interleukins Leishmaniasis Leishmaniasis, Mucocutaneous - genetics Leishmaniasis, Mucocutaneous - immunology Lesions Lymphocyte Activation - genetics Lymphocyte Activation - immunology Lymphocytes - immunology Medical sciences Microbiology Parasites Pathogenesis Reference Values T lymphocytes Th1 Cells - immunology Tissue samples
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Zusammenfassung:	Interleukin 17 (IL‐17) plays a critical role in inflammation and autoimmunity. Very little is known about IL‐17 in protozoa infection. Here, we show that lymphocytes obtained from patients with mucosal leishmaniasis and cutaneous leishmaniasis produce higher levels of IL‐17 than do lymphocytes obtained from uninfected control subjects (P
ISSN:	0022-1899 1537-6613
DOI:	10.1086/599380