Encapsulation and Sustained Release of Curcumin using Superparamagnetic Silica Reservoirs

For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic sh...

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Veröffentlicht in:	Chemistry : a European journal 2009-06, Vol.15 (23), p.5661-5665
Hauptverfasser:	Chin, Suk Fun, Iyer, K. Swaminathan, Saunders, Martin, St. Pierre, Tim G., Buckley, Craig, Paskevicius, Mark, Raston, Colin L.
Format:	Artikel
Sprache:	eng
Schlagworte:	curcumin Curcumin - administration & dosage drug delivery Drug Delivery Systems Ferric Compounds - chemical synthesis Ferric Compounds - chemistry Nanoparticles - therapeutic use silica capsule Silicon Dioxide - chemistry superparamagnetics sustained release Water
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Beschreibung
Zusammenfassung:	For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe3O4 particles surrounded by a silica matrix. For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe3O4 particles surrounded by a silica matrix.
ISSN:	0947-6539 1521-3765
DOI:	10.1002/chem.200802747