Improvement of islet culture with sericin

Improvement of islet culture with sericin

Islet transplantation is a promising treatment for diabetes. Serum is a necessary supplement in islet cultures, but it has various disadvantages including the risk of contamination by several pathogens. Results of this study suggest that sericin is a useful alternative supplement. Sericin accelerate...

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Veröffentlicht in:Journal of bioscience and bioengineering 2004, Vol.98 (3), p.217-219
Hauptverfasser: Ogawa, Akiko, Terada, Satoshi, Kanayama, Takanori, Miki, Masao, Morikawa, Mitsuhiro, Kimura, Toshihisa, Yamaguchi, Akio, Sasaki, Masahiro, Yamada, Hideyuki
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Biotechnology
BLOOD SERUM
CULTURE TECHNIQUES
DIABETES
Fundamental and applied biological sciences. Psychology
INSULIN
insulinoma
islet
PROTEINS
RATS
sericin
serum-free culture
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Zusammenfassung:Islet transplantation is a promising treatment for diabetes. Serum is a necessary supplement in islet cultures, but it has various disadvantages including the risk of contamination by several pathogens. Results of this study suggest that sericin is a useful alternative supplement. Sericin accelerated the proliferation of the rat insulinoma cell line RIN-5F and improved the serum-free culture of rat islets.
ISSN:1389-1723
1347-4421
DOI:10.1016/S1389-1723(04)00270-1