Changes of evoked epileptic seizures after the short term hypobaric hypoxia in the young rats

Changes of evoked epileptic seizures after the short term hypobaric hypoxia in the young rats

Exposition to the acute intensive hypobaric hypoxia blocks the triggering mechanism of epileptic seizures only within a short time interval after the end of hypoxia period and it does not influence the progressive epileptogenesis in 12-day-old rats. In 25-day-old rats' hypobaric hypoxia suppres...

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Veröffentlicht in:Prague medical report 2004, Vol.105 (4), p.381-390
1. Verfasser: Maresová, D
Format: Artikel
Sprache:eng
Schlagworte:
Age Factors
Air Pressure
Animals
Electric Stimulation
Epilepsy - complications
Epilepsy - physiopathology
Evoked Potentials, Somatosensory
Hypoxia - complications
Male
Rats
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Zusammenfassung:Exposition to the acute intensive hypobaric hypoxia blocks the triggering mechanism of epileptic seizures only within a short time interval after the end of hypoxia period and it does not influence the progressive epileptogenesis in 12-day-old rats. In 25-day-old rats' hypobaric hypoxia suppresses the postictal depression elicited by the repeated stimulation in short interstimulus intervals and it increases the duration of epileptic seizures evoked by electrical stimulation of the sensorimotor cortex.
ISSN:1214-6994