Synchronous mixed germ cell tumor of the pineal gland and suprasellar region with a predominant angiomatous component: a diagnostic challenge

We present a case of synchronous involvement of the pineal and suprasellar regions by a mixed germ cell tumor comprising germinoma and yolk sac tumor components, with a predominant angiomatous component. To our knowledge, it is the first case of this nature to be reported in the literature. Usually,...

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Veröffentlicht in:Journal of neuro-oncology 2009-06, Vol.93 (2), p.269-274
Hauptverfasser: Cunliffe, Clare H., Fischer, Ingeborg, Karajannis, Matthias, Monoky, David, Allen, Jeffrey, Wisoff, Jeffrey, Zagzag, David
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Sprache:eng
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Zusammenfassung:We present a case of synchronous involvement of the pineal and suprasellar regions by a mixed germ cell tumor comprising germinoma and yolk sac tumor components, with a predominant angiomatous component. To our knowledge, it is the first case of this nature to be reported in the literature. Usually, synchronous lesions of this kind are pure germinomas, and some clinicians will forgo a biopsy and assume a germinoma histology if the serum β-human chorionic gonadotrophin (HCG) is
ISSN:0167-594X
1573-7373
DOI:10.1007/s11060-008-9770-7