Free Leptin Is Associated With Masked Hypertension in Nonobese Subjects: A Cross-Sectional Study

Free Leptin Is Associated With Masked Hypertension in Nonobese Subjects: A Cross-Sectional Study

ABSTRACT—The aim of the study was to investigate whether diverse clinical blood pressure phenotypes are associated with free leptin surrogates, as reflected by plasma leptin, human soluble leptin receptor, and their ratio (ie, free leptin index) in nonobese normoglycemic subjects. Three separate cli...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 2009-06, Vol.53 (6), p.965-972
Hauptverfasser: Thomopoulos, Costas, Papadopoulos, Dimitris P, Papazachou, Ourania, Bratsas, Athanassios, Massias, Spiros, Anastasiadis, Georgios, Perrea, Despina, Makris, Thomas
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Analysis of Variance
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Biomarkers - blood
Blood and lymphatic vessels
Blood Pressure Determination - methods
Blood Pressure Monitoring, Ambulatory
Body Mass Index
Cardiology. Vascular system
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Cross-Sectional Studies
Echocardiography, Doppler
Enzyme-Linked Immunosorbent Assay
Female
Humans
Hypertension - blood
Hypertension - diagnosis
Hypertension - physiopathology
Leptin - blood
Leptin - metabolism
Linear Models
Logistic Models
Male
Medical sciences
Middle Aged
Multivariate Analysis
Probability
Reference Values
Sensitivity and Specificity
Severity of Illness Index
Ventricular Function, Left - physiology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:ABSTRACT—The aim of the study was to investigate whether diverse clinical blood pressure phenotypes are associated with free leptin surrogates, as reflected by plasma leptin, human soluble leptin receptor, and their ratio (ie, free leptin index) in nonobese normoglycemic subjects. Three separate clinic blood pressure measurements and ambulatory blood pressure monitoring were implemented to divide 494 subjects (aged 44±5 years; 272 men; body mass index
ISSN:0194-911X
1524-4563
DOI:10.1161/HYPERTENSIONAHA.108.128041