Application of lipases in kinetic resolution of racemates

Lipases have been well established as valuable catalysts in organic synthesis. This review article focuses on some of the recent developments in the rapidly growing field of lipase‐catalyzed kinetic resolution of racemates as a versatile method for the separation of enantiomers. The literature searc...

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Veröffentlicht in:	Chirality (New York, N.Y.) N.Y.), 2005, Vol.17 (1), p.1-15
Hauptverfasser:	Ghanem, Ashraf, Aboul-Enein, Hassan Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	biocatalysis chiral separation Chromatography, High Pressure Liquid Crystallization enantioselectivity Hydrolysis kinetic resolution Kinetics lipase Lipase - chemistry Organic Chemicals - chemistry Solvents - chemistry Stereoisomerism
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Beschreibung
Zusammenfassung:	Lipases have been well established as valuable catalysts in organic synthesis. This review article focuses on some of the recent developments in the rapidly growing field of lipase‐catalyzed kinetic resolution of racemates as a versatile method for the separation of enantiomers. The literature search dates back to the last five years and covers some comprehensive examples. The main emphasis is on the use of lipases in organic solvents. Chirality 17:1–15, 2005. © 2004 Wiley‐Liss, Inc.
ISSN:	0899-0042 1520-636X
DOI:	10.1002/chir.20089