Determinants of IV heparin treatment in patients with ischemic stroke

Management of acute ischemic stroke with IV unfractionated heparin is subject to debate. The authors evaluated patient-related and institutional factors influencing its use in 42 hospitals. Cardioembolic stroke type, carotid stenosis, atrial fibrillation, and treatment in stroke units or intensive c...

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Veröffentlicht in:	Neurology 2004-12, Vol.63 (12), p.2407-2409
Hauptverfasser:	SCHMIDT, W-P, HEUSCHMANN, P, TAEGER, D, HENNINGSEN, H, BUECKER-NOTT, H-J, BERGER, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Aged Anticoagulants - administration & dosage Anticoagulants - therapeutic use Atrial Fibrillation - complications Atrial Fibrillation - epidemiology Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Brain Ischemia - drug therapy Brain Ischemia - epidemiology Brain Ischemia - etiology Brain Ischemia - prevention & control Carotid Stenosis - complications Comorbidity Diabetes Complications - drug therapy Diabetes Complications - epidemiology Female Germany - epidemiology Guideline Adherence - statistics & numerical data Heart Diseases - complications Heparin - administration & dosage Heparin - therapeutic use Hospital Units - statistics & numerical data Humans Hypertension - complications Hypertension - epidemiology Infusions, Intravenous Intensive Care Units - statistics & numerical data Intracranial Embolism - drug therapy Intracranial Embolism - epidemiology Intracranial Embolism - etiology Male Medical sciences Middle Aged Neurology Organizational Policy Pharmacology. Drug treatments Practice Guidelines as Topic Recurrence Registries Vascular diseases and vascular malformations of the nervous system
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Zusammenfassung:	Management of acute ischemic stroke with IV unfractionated heparin is subject to debate. The authors evaluated patient-related and institutional factors influencing its use in 42 hospitals. Cardioembolic stroke type, carotid stenosis, atrial fibrillation, and treatment in stroke units or intensive care units significantly increased the probability of use. However, there are large unexplained variations in IV heparin use among hospitals.
ISSN:	0028-3878 1526-632X
DOI:	10.1212/01.WNL.0000147542.37657.2F