Partial Protection Induced by a BHV-1 Recombinant Vaccine against Challenge with BHV-5

: Bovine herpesvirus type 5 (BHV‐5) is the causative agent of bovine herpetic encephalitis, a major concern for cattle farming in Brazil and Argentina. We recently developed a differential, gE‐negative vaccine (265 gE‐), based on a Brazilian BHV‐1 strain. The present study was carried out to examine whether such a vaccine would confer protection to BHV‐5 infections. It was concluded that the recombinant BHV‐1 vaccine tested here is not capable of conferring full protection to BHV‐5 challenge.