CA-125 serum levels and pregnancy outcome in in vitro fertilization

CA-125 serum levels and pregnancy outcome in in vitro fertilization

This is a prospective cohort study of CA-125 levels drawn on the day of hCG administration in 386 women undergoing IVF treatment. The CA-125 levels were not helpful in determining pregnancy outcome, as indicated by poor sensitivity (40.8%) and specificity (52.7%), as well as an area under the receiv...

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Veröffentlicht in:Fertility and sterility 2004-12, Vol.82 (6), p.1705-1707
Hauptverfasser: Fish, Karen E., Phipps, Maureen, Trimarchi, James, Weitzen, Sherry, Blazar, Andrew S.
Format: Artikel
Sprache:eng
Schlagworte:
CA-125 Antigen - blood
Chorionic Gonadotropin - therapeutic use
Cohort Studies
Female
Fertilization in Vitro
Humans
Infertility, Female - therapy
Pregnancy - blood
Pregnancy Outcome
Prospective Studies
ROC Curve
Sensitivity and Specificity
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Beschreibung
Zusammenfassung:This is a prospective cohort study of CA-125 levels drawn on the day of hCG administration in 386 women undergoing IVF treatment. The CA-125 levels were not helpful in determining pregnancy outcome, as indicated by poor sensitivity (40.8%) and specificity (52.7%), as well as an area under the receiver operator characteristic curve close to 0.50.
ISSN:0015-0282
1556-5653
DOI:10.1016/j.fertnstert.2004.07.951