An Enantioselective Fluorescent Sensor for Sugar Acids

Chiral fluorescent boronic acid 1 was found to be a highly enantioselective, chemoselective, and sensitive sensor for sugar acids, such as tartaric acid. Enantioselectivities (K R/K S) of up to 550:1, chemoselectivity up to 11 000:1, and sensitivities in the micromolar range with sensor 1 were obser...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Chemical Society 2004-12, Vol.126 (49), p.16179-16186
Hauptverfasser:	Zhao, Jianzhang, Davidson, Matthew G, Mahon, Mary F, Kociok-Köhn, Gabriele, James, Tony D
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Boronic Acids - analysis Boronic Acids - chemistry Chemistry Crystallography, X-Ray Exact sciences and technology Fluorescent Dyes - chemical synthesis Fluorescent Dyes - chemistry Fluorescent Dyes - metabolism General, instrumentation Hydrogen-Ion Concentration Kinetics Models, Molecular Spectrometry, Fluorescence Stereoisomerism Sugar Acids - analysis Sugar Acids - chemistry Sugar Acids - metabolism Titrimetry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Chiral fluorescent boronic acid 1 was found to be a highly enantioselective, chemoselective, and sensitive sensor for sugar acids, such as tartaric acid. Enantioselectivities (K R/K S) of up to 550:1, chemoselectivity up to 11 000:1, and sensitivities in the micromolar range with sensor 1 were observed. Single-crystal X-ray analysis was used to confirm the structure of the fluorescent species.
ISSN:	0002-7863 1520-5126
DOI:	10.1021/ja046289s