The Nucleus Inside Out—Through a Rod Darkly

The Nucleus Inside Out—Through a Rod Darkly

In the nuclei of eukaryotic cells, euchromatin is located at the center, whereas heterochromatin is found at the periphery and is interspersed in the nucleoplasm. Solovei et al. (2009) now reveal that this normal pattern is reversed in the retinal rod cells of mice. This inversion might serve to max...

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Veröffentlicht in:Cell 2009-04, Vol.137 (2), p.205-207
Hauptverfasser: Ragoczy, Tobias, Groudine, Mark
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Nucleus - genetics
Euchromatin - chemistry
Heterochromatin - chemistry
Mice
Retinal Rod Photoreceptor Cells - cytology
Retinal Rod Photoreceptor Cells - physiology
Vision, Ocular
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Zusammenfassung:In the nuclei of eukaryotic cells, euchromatin is located at the center, whereas heterochromatin is found at the periphery and is interspersed in the nucleoplasm. Solovei et al. (2009) now reveal that this normal pattern is reversed in the retinal rod cells of mice. This inversion might serve to maximize light transmission to photoreceptors in nocturnal mammals.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2009.04.006