Natural infection of infants with respiratory syncytial virus subgroups A and b: A study of frequency, disease severity, and viral load

Heterogeneity in respiratory syncytial virus (RSV) disease severity likely is due to a combination of host and viral factors. Infection with RSV subgroup A is thought to produce more severe disease than RSV-B. Higher RSV loads correlate with greater disease severity in hospitalized infants. Whether...

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Veröffentlicht in:	Pediatric research 2004-12, Vol.56 (6), p.914-917
1. Verfasser:	DEVINCENZO, John P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal, Humanized Antiviral Agents - administration & dosage Biological and medical sciences Female General aspects Humans Infant Male Medical sciences Palivizumab Respiration, Artificial Respiratory Syncytial Virus Infections - drug therapy Respiratory Syncytial Virus Infections - immunology Respiratory Syncytial Virus Infections - virology Respiratory Syncytial Viruses - classification Respiratory Syncytial Viruses - growth & development Severity of Illness Index Viral Load
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Zusammenfassung:	Heterogeneity in respiratory syncytial virus (RSV) disease severity likely is due to a combination of host and viral factors. Infection with RSV subgroup A is thought to produce more severe disease than RSV-B. Higher RSV loads correlate with greater disease severity in hospitalized infants. Whether subgroup-specific variations in disease severity result from differences in RSV load has not been studied. A total of 102 RSV-hospitalized infants
ISSN:	0031-3998 1530-0447
DOI:	10.1203/01.PDR.0000145255.86117.6A