A New Glucosyl Feruloyl Quinic Acid as a Potential Marker for Roots and Rhizomes of Goldenseal, Hydrastis canadensis

A new compound, 5-O-(4'-[beta-d-glucopyranosyl]-trans-feruloyl)quinic acid (GPFQ, 10), is reported from the medicinal plant goldenseal (Hydrastis canadensis). A new HPLC method is described and used to show that GPFQ is a potential marker for goldenseal roots (1.0% w/w) and rhizomes (2.3%). GPF...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2004-11, Vol.67 (11), p.1818-1822
Hauptverfasser:	MCNAMARA, Catherine E., PERRY, Nigel B., FOLLETT, John M., PARMENTER, Graeme A., DOUGLAS, James A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Alkaloids - chemistry Alkaloids - isolation & purification Benzylisoquinolines Berberine Alkaloids - analysis Berberine Alkaloids - chemistry Berberine Alkaloids - isolation & purification Biological and medical sciences Biomarkers - analysis Chlorogenic Acid - analogs & derivatives Chlorogenic Acid - analysis Chlorogenic Acid - chemistry Chlorogenic Acid - isolation & purification Chlorogenic Acid - pharmacology Chromatography, High Pressure Liquid General pharmacology Hydrastis - chemistry Medical sciences Microbial Sensitivity Tests Molecular Structure New Zealand Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Roots - chemistry Plants, Medicinal - chemistry Rhizome - chemistry Staphylococcus aureus - drug effects
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Beschreibung
Zusammenfassung:	A new compound, 5-O-(4'-[beta-d-glucopyranosyl]-trans-feruloyl)quinic acid (GPFQ, 10), is reported from the medicinal plant goldenseal (Hydrastis canadensis). A new HPLC method is described and used to show that GPFQ is a potential marker for goldenseal roots (1.0% w/w) and rhizomes (2.3%). GPFQ was found at much lower levels in stems (
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np049868j