Transmural Oxygen Tension Gradients in Rat Cerebral Cortex Arterioles
Modified needle oxygen microelectrodes and vital microscopy were used to measure transmural oxygen tension gradients (PO 2 ) in pial arterioles with lumen diameters of 20–90 μm. A relationship between the magnitude of the transmural PO 2 gradient and arteriole wall tone was found: in control condit...
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| Veröffentlicht in: | Neuroscience and behavioral physiology 2009-05, Vol.39 (4), p.363-370 |
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| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Modified needle oxygen microelectrodes and vital microscopy were used to measure transmural oxygen tension gradients (PO
2
) in pial arterioles with lumen diameters of 20–90 μm. A relationship between the magnitude of the transmural PO
2
gradient and arteriole wall tone was found: in control conditions, PO
2
gradients were 1.17 ± 0.06 mmHg/μm (
n
= 40), while in conditions of arteriolar wall dilation the transmural PO
2
gradient decreased to 0.68 ± 0.04 mmHg/μm (
p
|
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| ISSN: | 0097-0549 1573-899X |
| DOI: | 10.1007/s11055-009-9142-6 |