Thymic stromal lymphopoietin as a mediator of crosstalk between bronchial smooth muscles and mast cells

Because the in vitro response of MCs to TSLP requires the presence of IL-1, we next show that the carryover of IL-1 in the BSM supernatant has a permissive role on the MC response to TSLP released by BSM cells (see Fig E2 in this article's Online Repository at www.jacionline.org).

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of allergy and clinical immunology 2009-04, Vol.123 (4), p.958-960.e2
Hauptverfasser:	Allakhverdi, Zoulfia, PhD, Comeau, Michael R., BSc, Jessup, Heidi K., BSc, Delespesse, Guy, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Allergy and Immunology Asthma Bronchi - cytology Cell Communication Cytokines Cytokines - physiology Humans Interleukin-1 - pharmacology Mast Cells - physiology Myocytes, Smooth Muscle - physiology Smooth muscle Tumor Necrosis Factor-alpha - pharmacology
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Beschreibung
Zusammenfassung:	Because the in vitro response of MCs to TSLP requires the presence of IL-1, we next show that the carryover of IL-1 in the BSM supernatant has a permissive role on the MC response to TSLP released by BSM cells (see Fig E2 in this article's Online Repository at www.jacionline.org).
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2009.01.059