Genetic variations of solute carrier family 30 (zinc transporter) member 8 ( SLC30A8 ) are not associated with polycystic ovary syndrome

No statistically significant differences in genotype and allele frequencies of single nucleotide polymorphism (SNP) rs13266634 in gene SLC30A8 were found between patients with polycystic ovary syndrome (PCOS) and healthy controls. No associations were observed between genotype of rs13266634 and the...

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Veröffentlicht in:	Fertility and sterility 2009-04, Vol.91 (4), p.1598-1601
Hauptverfasser:	Li, Li, M.D, Zhao, Yueran, M.D., Ph.D, Wang, Laicheng, M.S, Yan, Junhao, M.D, Chen, Zi-jiang, M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Case-Control Studies Cation Transport Proteins - genetics Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Female genital diseases Gene Frequency - genetics Genetic Predisposition to Disease - genetics Genotype Gynecology. Andrology. Obstetrics Humans insulin secretion Internal Medicine Medical sciences Non tumoral diseases Obstetrics and Gynecology Polycystic ovary syndrome Polycystic Ovary Syndrome - genetics Polymorphism, Single Nucleotide - genetics single nucleotide polymorphism SLC30A8 type 2 diabetes mellitus Zinc Transporter 8
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Zusammenfassung:	No statistically significant differences in genotype and allele frequencies of single nucleotide polymorphism (SNP) rs13266634 in gene SLC30A8 were found between patients with polycystic ovary syndrome (PCOS) and healthy controls. No associations were observed between genotype of rs13266634 and the quantitative clinical features of PCOS patients in the PCOS group after adjustment for body mass index.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/j.fertnstert.2008.11.004