Two Unusual Naphthalene-Containing Compounds from a Freshwater Fungus YMF 1.01029

Two novel naphthalene‐containing compounds, colelomycerones A and B (1 and 2, resp.), and three known metabolites, including preussomerin D (3), (2RS,2′SR,3′E,3SR,4E,8E)‐1‐O‐(β‐D‐glucopyranosyl)‐3‐hydroxy‐2‐[(2‐hydroxyoctadec‐3‐enoyl)amino]‐9‐methyloctadeca‐4,8‐diene (4), and 3β‐hydroxy‐5α,8α‐epidioxyergosta‐6,22‐diene (5), were isolated from the culture broth of an unidentified freshwater water fungus YMF 1.01029. This fungus was collected from a decaying branch of an unidentified tree near Lake Fuxian in Yunnan Province, China. The structures of these five compounds were determined on the basis of their spectroscopic and mass‐spectrometric data. Colelomycerones A and B (1 and 2, resp.) represent unprecendented examples of naphthalene‐1,2‐diones with novel cyclic acetals. Compounds 1–3 showed noticeable antifungal and antibacterial activities.