Plaque Characteristics in Culprit Lesions and Inflammatory Status in Diabetic Acute Coronary Syndrome Patients

Plaque Characteristics in Culprit Lesions and Inflammatory Status in Diabetic Acute Coronary Syndrome Patients Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Yoon, Kye Hun Kim, Hyung Woo...

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Veröffentlicht in:	JACC. Cardiovascular imaging 2009-03, Vol.2 (3), p.339-349
Hauptverfasser:	Hong, Young Joon, MD, PhD, Jeong, Myung Ho, MD, PhD, FACC, FAHA, FESC, FSCAI, Choi, Yun Ha, RN, Ko, Jum Suk, MD, Lee, Min Goo, MD, Kang, Won Yu, MD, Lee, Shin Eun, MD, Kim, Soo Hyun, MD, Park, Keun Ho, MD, Sim, Doo Sun, MD, Yoon, Nam Sik, MD, Yoon, Hyun Ju, MD, Kim, Kye Hun, MD, PhD, Park, Hyung Wook, MD, PhD, Kim, Ju Han, MD, PhD, Ahn, Youngkeun, MD, PhD, FACC, FSCAI, Cho, Jeong Gwan, MD, PhD, FACC, Park, Jong Chun, MD, PhD, Kang, Jung Chaee, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - blood Acute Coronary Syndrome - diagnostic imaging Aged Biomarkers - blood C-Reactive Protein - analysis Cardiovascular Coronary Angiography Coronary Artery Disease - blood Coronary Artery Disease - diagnostic imaging Diabetic Angiopathies - blood Diabetic Angiopathies - diagnostic imaging Female Humans Inflammation - blood Inflammation - diagnostic imaging Inflammation Mediators - blood Male Middle Aged Necrosis Odds Ratio Predictive Value of Tests Retrospective Studies Risk Assessment Rupture Ultrasonography, Interventional User-Computer Interface
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Zusammenfassung:	Plaque Characteristics in Culprit Lesions and Inflammatory Status in Diabetic Acute Coronary Syndrome Patients Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Yoon, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang To determine the characteristics of culprit lesions in diabetic patients with acute coronary syndrome (ACS), intravascular ultrasound and virtual histology-intravascular ultrasound were performed in a large series of patients with ACS. Diabetic patients had greater hs-CRP, multivessel disease, and plaque burden. In the acute myocardial infarction patients, diabetics had more multiple plaque ruptures and thrombus. Diabetic patients also had greater necrotic core volumes and greater incidence of thin-cap fibroatheromas. Therefore, the diabetic patients with ACS have more characteristics of plaque vulnerability and elevated inflammatory state compared with nondiabetic patients with ACS.
ISSN:	1936-878X 1876-7591
DOI:	10.1016/j.jcmg.2008.10.017