Low Sensitivity of Rapid Diagnostic Test for Influenza

The QuickVue Influenza A+B Test (Quidel) was used to test nasal swab specimens obtained from persons with influenza-like illness in 3 different populations. Compared with reverse-transcriptase polymerase chain reaction, the test sensitivity was low for all populations (median, 27%; range, 19%–32%),...

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Veröffentlicht in:	Clinical infectious diseases 2009-05, Vol.48 (9), p.e89-e92
Hauptverfasser:	Uyeki, Timothy M., Prasad, Ramakrishna, Vukotich, Charles, Stebbins, Samuel, Rinaldo, Charles R., Ferng, Yu-hui, Morse, Stephen S., Larson, Elaine L., Aiello, Allison E., Davis, Brian, Monto, Arnold S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Child Child, Preschool Humans Immunoassay - methods Infant Influenza A virus - isolation & purification Influenza B virus - isolation & purification Influenza, Human - diagnosis Middle Aged Nasal Mucosa - virology Reagent Kits, Diagnostic Reverse Transcriptase Polymerase Chain Reaction Sensitivity and Specificity Young Adult
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Beschreibung
Zusammenfassung:	The QuickVue Influenza A+B Test (Quidel) was used to test nasal swab specimens obtained from persons with influenza-like illness in 3 different populations. Compared with reverse-transcriptase polymerase chain reaction, the test sensitivity was low for all populations (median, 27%; range, 19%–32%), whereas the specificity was high (median, 97%; range, 96%–99.6%).
ISSN:	1058-4838 1537-6591
DOI:	10.1086/597828