Memory complaints in nondemented men predict future pathologic diagnosis of Alzheimer disease

The validity of memory complaints as a predictor of Alzheimer disease (AD) was assessed in 237 Japanese-American men autopsied at ages 74 to 97 years. These men were free of dementia at the time memory complaints were assessed 1 to 11 years earlier. Memory complaints were found to predict the neurop...

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Veröffentlicht in:	Neurology 2004-11, Vol.63 (10), p.1960-1961
Hauptverfasser:	JORM, A. F, MASAKI, K. H, DAVIS, D. G, HARDMAN, J, NELSON, J, MARKESBERY, W. R, PETROVITCH, H, ROSS, G. W, WHITE, L. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - diagnosis Alzheimer Disease - epidemiology Appointments and Schedules Asian Americans Biological and medical sciences Cohort Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Depression - epidemiology Disease Progression Educational Status Face Follow-Up Studies Hawaii - epidemiology Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Logistic Models Male Medical sciences Memory Disorders - epidemiology Names Nervous system (semeiology, syndromes) Neurology Odds Ratio Prospective Studies Psychological Tests Risk Factors
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Zusammenfassung:	The validity of memory complaints as a predictor of Alzheimer disease (AD) was assessed in 237 Japanese-American men autopsied at ages 74 to 97 years. These men were free of dementia at the time memory complaints were assessed 1 to 11 years earlier. Memory complaints were found to predict the neuropathologic diagnosis of AD after adjusting for age, time to death, education, depression, and cognitive functioning.
ISSN:	0028-3878 1526-632X
DOI:	10.1212/01.WNL.0000144348.70643.F2