Controllable Peptide-Dendron Self-Assembly: Interconversion of Nanotubes and Fibrillar Nanostructures

Controllable Peptide-Dendron Self-Assembly: Interconversion of Nanotubes and Fibrillar Nanostructures

Roll up: A peptide-dendron hybrid (PDH) is capable of self-assembling into either a soluble nanotube or an amyloid-like fibrillar network. The structures interconvert on adjusting the salt concentration or pH value. Their hydrophobic interfaces efficiently encapsulate hydrophobic molecules in water...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2009-01, Vol.48 (14), p.2525-2528
Hauptverfasser: Shao, Hui, Parquette, Jon R
Format: Artikel
Sprache:eng
Schlagworte:
Amyloid - chemistry
Anthracenes - chemistry
dendrons
Hydrogen-Ion Concentration
Hydrophobic and Hydrophilic Interactions
Microscopy, Atomic Force
nanofibrils
Nanostructures - chemistry
Nanostructures - ultrastructure
nanotubes
Nanotubes - chemistry
peptides
Peptides - chemistry
Salts - chemistry
self‐assembly
Surface Properties
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Beschreibung
Zusammenfassung:Roll up: A peptide-dendron hybrid (PDH) is capable of self-assembling into either a soluble nanotube or an amyloid-like fibrillar network. The structures interconvert on adjusting the salt concentration or pH value. Their hydrophobic interfaces efficiently encapsulate hydrophobic molecules in water which can then be released by lowering the pH value.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200805010