Ascended testis in three brothers with Pelizaeus Merzbacher syndrome

Ascended testis is a rare clinical entity. The mechanism involved in testicular ascent is still not understood completely. Spasticity of cremaster muscle may cause secondary ascent of testis. The authors present 3 brothers with Pelizaeus Merzbacher syndrome, a rare, x-linked leukodystrophy in whom the testes bilaterally ascended from the normal scrotal position to an undescended position after onset of spasticity.