Exhaustion and coronary heart disease: the history of a scientific quest

This paper describes the development of the concept “vital exhaustion”, the epidemiological evidence that this state belongs to the precursors of different manifestations of coronary artery disease, and the biological plausibility of the association between exhaustion and coronary artery disease. It...

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Veröffentlicht in:	Patient education and counseling 2004-11, Vol.55 (2), p.223-229
1. Verfasser:	Appels, Ad
Format:	Artikel
Sprache:	eng
Schlagworte:	Behavioural intervention Coronary artery disease Coronary Disease - etiology Coronary Disease - physiopathology Coronary Disease - prevention & control Corticotropin-Releasing Hormone - physiology Depression - complications Depression - prevention & control Exhaustion Fatigue - complications Fatigue - prevention & control Hostility HPA-axis Humans Hypothalamo-Hypophyseal System - physiopathology Inflammation Irritable Mood Life Style Male Nursing Pituitary-Adrenal System - physiopathology Program Evaluation Recurrence Relaxation Therapy - standards Risk Factors Self-Help Groups - organization & administration Stress, Psychological - complications Stress, Psychological - prevention & control Treatment Outcome Type A Personality
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Beschreibung
Zusammenfassung:	This paper describes the development of the concept “vital exhaustion”, the epidemiological evidence that this state belongs to the precursors of different manifestations of coronary artery disease, and the biological plausibility of the association between exhaustion and coronary artery disease. It further describes the main results of a randomized, controlled trial designed to determine whether a behavioural intervention reduces the risk of a new coronary event.
ISSN:	0738-3991 1873-5134
DOI:	10.1016/j.pec.2003.09.008