Anti-TNF-alpha therapy for chronic inflammation: reconsidering pentoxifylline as an alternative to therapeutic protein drugs

Pentoxifylline is a useful inhibitor of TNF-alpha production, thus resembling anti-inflammatory corticosteroids. The combination of pentoxifylline with Lyprinol is an effective treatment for chronic inflammation in rats, in this respect mimicking low dose prednisone with Lyprinol.

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Veröffentlicht in:Inflammopharmacology 2004, Vol.12 (3), p.223-227
1. Verfasser: Whitehouse, M W
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creator Whitehouse, M W
description Pentoxifylline is a useful inhibitor of TNF-alpha production, thus resembling anti-inflammatory corticosteroids. The combination of pentoxifylline with Lyprinol is an effective treatment for chronic inflammation in rats, in this respect mimicking low dose prednisone with Lyprinol.
doi_str_mv 10.1163/1568560042342293
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subjects Animals
Chronic Disease
Humans
Inflammation - drug therapy
Lipids - therapeutic use
Pentoxifylline - therapeutic use
Rats
Tumor Necrosis Factor-alpha - antagonists & inhibitors
title Anti-TNF-alpha therapy for chronic inflammation: reconsidering pentoxifylline as an alternative to therapeutic protein drugs
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