Anti-TNF-alpha therapy for chronic inflammation: reconsidering pentoxifylline as an alternative to therapeutic protein drugs

Pentoxifylline is a useful inhibitor of TNF-alpha production, thus resembling anti-inflammatory corticosteroids. The combination of pentoxifylline with Lyprinol is an effective treatment for chronic inflammation in rats, in this respect mimicking low dose prednisone with Lyprinol.

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Bibliographische Detailangaben
Veröffentlicht in:	Inflammopharmacology 2004, Vol.12 (3), p.223-227
1. Verfasser:	Whitehouse, M W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chronic Disease Humans Inflammation - drug therapy Lipids - therapeutic use Pentoxifylline - therapeutic use Rats Tumor Necrosis Factor-alpha - antagonists & inhibitors
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Beschreibung
Zusammenfassung:	Pentoxifylline is a useful inhibitor of TNF-alpha production, thus resembling anti-inflammatory corticosteroids. The combination of pentoxifylline with Lyprinol is an effective treatment for chronic inflammation in rats, in this respect mimicking low dose prednisone with Lyprinol.
ISSN:	0925-4692 1568-5608
DOI:	10.1163/1568560042342293