Patterns of recruitment into acute myeloid leukaemia (AML) 15 and outcome for young patients with AML at a single referral centre

Patterns of recruitment into acute myeloid leukaemia (AML) 15 and outcome for young patients with AML at a single referral centre

Summary This study assessed the recruitment to an acute myeloid leukaemia (AML) trial (AML15) in a single centre, evaluated whether outcome was influenced by trial entry and whether the trial population could be considered representative of all AML patients by retrospective comparison of patient cha...

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Veröffentlicht in:British journal of haematology 2009-04, Vol.145 (1), p.40-44
Hauptverfasser: Stevens, Jane M., MacDougall, Finlay, Jenner, Michael, Oakervee, Heather, Cavenagh, Jamie, Lister, Andrew T.
Format: Artikel
Sprache:eng
Schlagworte:
acute myeloid leukaemia
Adolescent
Adult
Age Factors
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
clinical trial
Clinical Trials, Phase III as Topic
Female
Hematologic and hematopoietic diseases
Humans
Leukemia, Myeloid, Acute - drug therapy
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Middle Aged
Patient Selection
Randomized Controlled Trials as Topic
Remission Induction
Selection Bias
Treatment Outcome
trial recruitment
Young Adult
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Zusammenfassung:Summary This study assessed the recruitment to an acute myeloid leukaemia (AML) trial (AML15) in a single centre, evaluated whether outcome was influenced by trial entry and whether the trial population could be considered representative of all AML patients by retrospective comparison of patient characteristics, trial entry and outcome for 81 consecutive patients (
ISSN:0007-1048
1365-2141
DOI:10.1111/j.1365-2141.2008.07561.x