Matrix metalloproteinases and the gut — new roles for old enzymes
Matrix metalloproteinases (MMPs) are a family of neutral proteases with the ability to degrade all components of extracellular matrix. To date, more than 24 different human MMPs have been identified. MMP activity is important in diseases such as arthritis, atherosclerosis, periodontal diseases and c...
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| Veröffentlicht in: | Current opinion in pharmacology 2004-12, Vol.4 (6), p.546-550 |
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| creator | Pender, Sylvia LF MacDonald, Thomas T |
| description | Matrix metalloproteinases (MMPs) are a family of neutral proteases with the ability to degrade all components of extracellular matrix. To date, more than 24 different human MMPs have been identified. MMP activity is important in diseases such as arthritis, atherosclerosis, periodontal diseases and cancer. Recent data suggest that MMPs are involved in tissue injury and healing in the human gut. |
| doi_str_mv | 10.1016/j.coph.2004.06.005 |
| format | Article |
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| subjects | Extracellular Matrix - drug effects Extracellular Matrix - metabolism Gastrointestinal Diseases - enzymology Gastrointestinal Tract - enzymology Humans Matrix Metalloproteinases - metabolism Matrix Metalloproteinases - pharmacology United Kingdom |
| title | Matrix metalloproteinases and the gut — new roles for old enzymes |
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