Neuropathology: Many Paths Lead to Hereditary Spastic Paraplegia

Studies with animal models are providing new insights into the pathology of hereditary spastic paraplegia, particularly how mutations in multiple, converging pathways can lead to this family of neuropathies.

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Bibliographische Detailangaben
Veröffentlicht in:	Current biology 2004-10, Vol.14 (20), p.R903-R904
Hauptverfasser:	Gould, Robert M., Brady, Scott T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Axons - metabolism Humans Microtubules - metabolism Mutation - genetics Myelin Proteins - genetics Myelin Proteins - metabolism Neuroglia - metabolism Spastic Paraplegia, Hereditary - genetics Spastic Paraplegia, Hereditary - metabolism Spastic Paraplegia, Hereditary - pathology Spastin Synaptic Vesicles - metabolism
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Beschreibung
Zusammenfassung:	Studies with animal models are providing new insights into the pathology of hereditary spastic paraplegia, particularly how mutations in multiple, converging pathways can lead to this family of neuropathies.
ISSN:	0960-9822 1879-0445
DOI:	10.1016/j.cub.2004.09.076