Russujaponols G—L, Illudoid Sesquiterpenes, and Their Neurite Outgrowth Promoting Activity from the Fruit Body of Russula japonica

Six new illudoid sesquiterpene, russujaponols G—L (1—6) were isolated from the fruit bodies of Russula japonica. Their structures were established primarily by 2D NMR experiments. Furthermore, russujaponols I—K showed neurite outgrowth promoting activity in the primary cultured rat cortical neurons....

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 2009/03/01, Vol.57(3), pp.311-314
Hauptverfasser:	Yoshikawa, Kazuko, Matsumoto, Yuki, Hama, Hiroshi, Tanaka, Masami, Zhai, Haifeng, Fukuyama, Yoshiyasu, Arihara, Shigenobu, Hashimoto, Toshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basidiomycota - chemistry Cells, Cultured Fruit - chemistry illudoid sesquiterpene neurite outgrowth promoting activity Neurites - drug effects Rats russujaponol Russula Russula japonica Russulaceae Sesquiterpenes - chemistry Sesquiterpenes - isolation & purification Sesquiterpenes - pharmacology
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Zusammenfassung:	Six new illudoid sesquiterpene, russujaponols G—L (1—6) were isolated from the fruit bodies of Russula japonica. Their structures were established primarily by 2D NMR experiments. Furthermore, russujaponols I—K showed neurite outgrowth promoting activity in the primary cultured rat cortical neurons.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.57.311