The state of cerebral hemodynamics in conditions of prolonged adaptation to hypercapnic hypoxia

Intermittent hypercapnic hypoxia was accompanied by increases in cerebral vascular resistance, decreases in the reactivity of cerebral vessels to hypercapnia, and increases in the collateral reserve and rate of autoregulation of brain blood flow. These changes were an important component of the mech...

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Veröffentlicht in:	Neuroscience and behavioral physiology 2009-03, Vol.39 (3), p.269-273
Hauptverfasser:	Kulikov, V. P., Bespalov, A. G., Yakushev, N. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Adult Behavioral Sciences Biomedical and Life Sciences Biomedicine Blood Flow Velocity - physiology Cerebrovascular Circulation - physiology Female Gases Hemodynamics Humans Hypercapnia - physiopathology Hypoxia Hypoxia - physiopathology Middle Cerebral Artery - physiology Neurobiology Neurosciences Physiology Time Factors Veins & arteries
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Zusammenfassung:	Intermittent hypercapnic hypoxia was accompanied by increases in cerebral vascular resistance, decreases in the reactivity of cerebral vessels to hypercapnia, and increases in the collateral reserve and rate of autoregulation of brain blood flow. These changes were an important component of the mechanism increasing the tolerance of the brain to ischemia in response to training with hypercapnic hypoxia.
ISSN:	0097-0549 1573-899X
DOI:	10.1007/s11055-009-9121-y