The neuroscience of tinnitus

Tinnitus is an auditory phantom sensation (ringing of the ears) experienced when no external sound is present. Most but not all cases are associated with hearing loss induced by noise exposure or aging. Neuroscience research has begun to reveal how tinnitus is generated by the brain when hearing los...

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Veröffentlicht in:	Trends in neurosciences (Regular ed.) 2004-11, Vol.27 (11), p.676-682
Hauptverfasser:	Eggermont, Jos J., Roberts, Larry E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain Cerebral Cortex - physiology Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Ears & hearing Fundamental and applied biological sciences. Psychology Humans Medical sciences Nerve Net - physiology Neurology Neurons Non tumoral diseases Otorhinolaryngology. Stomatology Tinnitus Tinnitus - physiopathology Tinnitus - therapy Vertebrates: nervous system and sense organs
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Beschreibung
Zusammenfassung:	Tinnitus is an auditory phantom sensation (ringing of the ears) experienced when no external sound is present. Most but not all cases are associated with hearing loss induced by noise exposure or aging. Neuroscience research has begun to reveal how tinnitus is generated by the brain when hearing loss occurs, and to suggest new avenues for management and prevention of tinnitus following hearing injuries. Downregulation of intracortical inhibition induced by damage to the cochlea or to auditory projection pathways highlights neural processes that underlie the sensation of phantom sound.
ISSN:	0166-2236 1878-108X
DOI:	10.1016/j.tins.2004.08.010