Ninety-Six—Week Efficacy of Combination Therapy with Lamivudine and Tenofovir in Patients Coinfected with HIV-1 and Wild-Type Hepatitis B Virus

We describe 6 patients who were coinfected with human immunodeficiency virus (HIV) type 1 and wild-type hepatitis B virus (HBV), in whom complete and sustained antiviral activity against wild-type HBV strains was attained during 96 weeks of combination therapy with lamivudine and tenofovir. The use...

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Veröffentlicht in:Clinical infectious diseases 2004-10, Vol.39 (7), p.1062-1064
Hauptverfasser: Bani-Sadr, F., Palmer, P., Scieux, C., Molina, J. M.
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container_end_page 1064
container_issue 7
container_start_page 1062
container_title Clinical infectious diseases
container_volume 39
creator Bani-Sadr, F.
Palmer, P.
Scieux, C.
Molina, J. M.
description We describe 6 patients who were coinfected with human immunodeficiency virus (HIV) type 1 and wild-type hepatitis B virus (HBV), in whom complete and sustained antiviral activity against wild-type HBV strains was attained during 96 weeks of combination therapy with lamivudine and tenofovir. The use of combination therapy with lamivudine and tenofovir for the treatment of HBV infection is very promising in the treatment of HIV/HBV coinfection.
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subjects Adenine - analogs & derivatives
Adenine - therapeutic use
Adult
AIDS
Anti-HIV Agents - therapeutic use
Antibodies
Biological and medical sciences
DNA
Drug Therapy, Combination
Female
Hepatitis antigens
Hepatitis B
Hepatitis B - complications
Hepatitis B - drug therapy
Hepatitis B virus
HIV
HIV 1
HIV Infections - complications
HIV Infections - drug therapy
HIV/AIDS
Human immunodeficiency virus 1
Human viral diseases
Humans
Infections
Infectious diseases
Lamivudine - therapeutic use
Male
Medical sciences
Middle Aged
Organophosphonates - therapeutic use
RNA
Tenofovir
Viral diseases
Viral diseases of the digestive system
Viral diseases of the lymphoid tissue and the blood. Aids
Viral hepatitis
title Ninety-Six—Week Efficacy of Combination Therapy with Lamivudine and Tenofovir in Patients Coinfected with HIV-1 and Wild-Type Hepatitis B Virus
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