Cortical Development deNUDEd

Cortical Development deNUDEd

The development of the cerebral cortex is a highly orchestrated process of cell division and migration. In this issue of Neuron, Feng and Walsh and Shu et al. examine the roles of two related proteins, Nde1 (mNudE) and Ndel1 (NUDEL), in cortical development. These proteins play a crucial role in cen...

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Veröffentlicht in:Neuron 2004-10, Vol.44 (2), p.213-214
1. Verfasser: Schaar, Bruce T.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Carrier Proteins - physiology
Cell cycle
Cell division
Cerebral Cortex - embryology
Defects
Humans
Mammals
Neurons
Neurosciences
Proteins
Studies
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Zusammenfassung:The development of the cerebral cortex is a highly orchestrated process of cell division and migration. In this issue of Neuron, Feng and Walsh and Shu et al. examine the roles of two related proteins, Nde1 (mNudE) and Ndel1 (NUDEL), in cortical development. These proteins play a crucial role in centrosome positioning, with Nde1 functioning mainly during progenitor cell divisions and Ndel1 functioning in neuronal migration.
ISSN:0896-6273
1097-4199
DOI:10.1016/j.neuron.2004.10.002