Wide channel dielectrophoresis-based particle exchanger with electrophoretic diffusion compensation

We present here a microfluidic device for the chemical modification of particles. In order to alleviate diffusive mixing issues beads are pushed from a starting buffer to a reagent over a wide channel by an array of shifted electrodes. We also show that the effect of reagent diffusion can be compens...

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Veröffentlicht in:Lab on a chip 2009-01, Vol.9 (5), p.657-660
Hauptverfasser: Tornay, Raphaël, Braschler, Thomas, Renaud, Philippe
Format: Artikel
Sprache:eng
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Zusammenfassung:We present here a microfluidic device for the chemical modification of particles. In order to alleviate diffusive mixing issues beads are pushed from a starting buffer to a reagent over a wide channel by an array of shifted electrodes. We also show that the effect of reagent diffusion can be compensated by electrophoretic forces.
ISSN:1473-0197
1473-0189
DOI:10.1039/b816043k