Development of a Ruthenium-Catalyzed Asymmetric Epoxidation Procedure with Hydrogen Peroxide as the Oxidant

Development of a Ruthenium-Catalyzed Asymmetric Epoxidation Procedure with Hydrogen Peroxide as the Oxidant

Novel pyboxazines and the known pybox ligands are used in the ruthenium‐catalyzed asymmetric epoxidation of olefins with H2O2 (see scheme). This new catalytic system is successful in the conversion of differently substituted aromatic olefins and gives ee values of up to 84 %.

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Veröffentlicht in:Angewandte Chemie International Edition 2004-10, Vol.43 (39), p.5255-5260
Hauptverfasser: Tse, Man Kin, Döbler, Christian, Bhor, Santosh, Klawonn, Markus, Mägerlein, Wolfgang, Hugl, Herbert, Beller, Matthias
Format: Artikel
Sprache:eng
Schlagworte:
asymmetric catalysis
epoxidations
homogeneous catalysis
ruthenium
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Zusammenfassung:Novel pyboxazines and the known pybox ligands are used in the ruthenium‐catalyzed asymmetric epoxidation of olefins with H2O2 (see scheme). This new catalytic system is successful in the conversion of differently substituted aromatic olefins and gives ee values of up to 84 %.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200460528