Renal amyloidosis in juvenile rheumatoid arthritis

We report a case of a rare disorder of renal amyloidosis occurring as a complication of juvenile rheumatoid arthritis in a 16-year-old adolescent male. He presented with generalized edema and hypertension. The laboratory work-up showed nephrotic-range proteinuria and hypoalbuminemia and normal renal...

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Veröffentlicht in:Journal of the College of Physicians and Surgeons--Pakistan 2009-02, Vol.19 (2), p.130-132
Hauptverfasser: Akhtar, Naureen, Kiran, Sadia, Hussain, Abid, Suleman, Bilquis A, Jaleel, Shahila
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Sprache:eng
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Zusammenfassung:We report a case of a rare disorder of renal amyloidosis occurring as a complication of juvenile rheumatoid arthritis in a 16-year-old adolescent male. He presented with generalized edema and hypertension. The laboratory work-up showed nephrotic-range proteinuria and hypoalbuminemia and normal renal function despite bilateral shrunken kidneys revealed by the abdominal ultrasound. His renal biopsy showed deposition of amyloid fibrils in the form of homogenous eosinophilic material within the glomeruli demonstrating the pathognomonic apple-green birefringence by polarized light microscopy.
ISSN:1022-386X