Influence of Overnight Orthokeratology on Corneal Endothelium

PURPOSETo evaluate the influence of overnight orthokeratology on the corneal endothelium. METHODSFifty-two eyes of 31 patients undergoing overnight orthokeratology for myopia were examined. They wore the lens every night and were followed up for at least 1 year. The corneal endothelium was examined...

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Veröffentlicht in:Cornea 2004-11, Vol.23 (8 Suppl 1), p.S82-S86
Hauptverfasser: Hiraoka, Takahiro, Furuya, Airi, Matsumoto, Yujiro, Okamoto, Fumiki, Kakita, Tetsuhiko, Oshika, Tetsuro
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Sprache:eng
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Zusammenfassung:PURPOSETo evaluate the influence of overnight orthokeratology on the corneal endothelium. METHODSFifty-two eyes of 31 patients undergoing overnight orthokeratology for myopia were examined. They wore the lens every night and were followed up for at least 1 year. The corneal endothelium was examined with specular microscopy to calculate mean endothelial cell density, coefficient of variation of cell area, and percentage of hexagonal cells. Data obtained at 1-year follow-up examinations were compared with those at the baseline examinations using a paired t test. RESULTSOrthokeratology significantly reduced manifest refraction from −2.32 ± 1.18 D (mean ± standard deviation) to −0.16 ± 0.33 D (P < 0.0001) and improved uncorrected visual acuity from 0.77 ± 0.29 to −0.07 ± 0.10 logMAR (P < 0.0001). The endothelial cell density did not change significantly (2879 ± 231 cells/mm before and 2864 ± 260 cells/mm after treatment, P = 0.252). The coefficient of variation of cell area was 22.3 ± 2.7 at baseline and 22.1 ± 2.4 at 1-year posttreatment, which did not change significantly (P = 0.537). The percentage of hexagonal cells was 72.8 ± 10.2% pretreatment and 72.5 ± 10.9% posttreatment (P = 0.800). CONCLUSIONSOvernight orthokeratology for 1 year did not influence the density or morphology of corneal endothelial cells.
ISSN:0277-3740
1536-4798
DOI:10.1097/01.ico.0000136688.97898.94